Contouring library
The following bibliography of published peer reviewed articles includes uses for our
technology that may not have been specifically cleared or evaluated by the FDA.
See the bottom of the page for indications for use and warnings.
Roundtable Discussion: Making Sense of Current Liposuction Technologies
Cook J, Pozner JN, Turer DM, et al. Roundtable Discussion: Making Sense of Current Liposuction Technologies. Aesthet Surg J Open Forum. 2021;4:ojab045. Published 2021 Nov 9. doi:10.1093/asjof/ojab045
Enhanced Lipocontouring of the Arms
Khanna, J., & Saheb-Al-Zamani, M. (2021). Enhanced Lipocontouring of the Arms. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.98807
A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms
Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.
Enhanced Abdominal Contouring
Kleban, S. R. , Bharti, G., & Kortesis, B. G. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398
Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network
Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849
New Technologies in Skin Tightening
Malone, C.H., Walters, N., Stroh, R. et al. New Technologies in Skin Tightening. Curr Otorhinolaryngol Rep 9, 422–435 (2021). https://doi.org/10.1007/s40136-021-00371-5
A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion®
Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.
Helium Plasma-Assisted Breast Reduction: A Pilot Study
Seraphine Moncada, BS, Christopher Nichols, MD, Helium Plasma-Assisted Breast Reduction: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac041, https://doi.org/10.1093/asjof/ojac041
A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology
Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32
Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency
Neinstein R, Funderburk CD. Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency. Advances in Cosmetic Surgery, Volume 3, Issue 1, 2020, Pages 173-188, ISSN 2542-4327, ISBN 9780323778282. https://doi.org/10.1016/j.yacs.2020.01.012.
Combining Helium Plasma-Driven Radiofrequency with Nanofat for Contouring
Duncan, Diane. (2020). Combining Helium Plasma-Driven Radiofrequency with Nanofat for Contouring. 10.5772/intechopen.91611.
The Use of Cold Atmospheric Plasma Device in Flap Elevation
Pinelli M, Starnoni M, De Santis G. The Use of Cold Atmospheric Plasma Device in Flap Elevation. Plast Reconstr Surg Glob Open 2020;8:e2815; doi: 10.1097/GOX.0000000000002815
The future of skin tightening: Mechanical or biological?
Duncan, DI. The future of skin tightening: Mechanical or biological? Dermatological Reviews. 2020; 1: 128- 137. https://doi.org/10.1002/der2.40
Thermal Effects of Percutaneous Application of Plasma/Radiofrequency Energy on Porcine Dermis & Fibroseptal Network
Ruff IV, PG. Thermal Effects of Percutaneous Application of Plasma/Radiofrequency Energy on Porcine Dermis & Fibroseptal Network. JCD, 2020. DOI: 10.1111/jocd.13845
Helium Plasma Subdermal Tissue Contraction Method of Action
Duncan DI, Roman, S. Helium Plasma Subdermal Tissue Contraction Method of Action. BioMedical Journal of Scientific & Technical Research. October 19, 2020; DOI: 10.26717/BJSTR.2020.31.005075.
A Prospective Multicenter, Evaluator-Blinded Study Evaluating the Safety and Effectiveness of the Renuvion® APR Device to Improve the Appearance of Lax Tissue in the Neck and Submental Region
Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. A Prospective Multicenter, Evaluator-Blinded Study Evaluating the Safety and Effectiveness of the Renuvion APR Device to Improve the Appearance of Lax Tissue in the Neck and Submental Region. ISAPS 2022.
Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck
Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.
Safety and efficacy of helium plasma for subdermal coagulation
Ruff IV, PG, Doolabh V, Zimmerman E, Gentile R. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews 2020; 1-7. https://doi.org/10.1002/der2.34
Renuvion®/J-Plasma® for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck
Gentile RD. Renuvion/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001
Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction
Paul Ruff, MD, Paul Vanek, MD, Matthew Nykiel, MD, Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064
Renuvion® RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck
Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.
The Safety and Efficacy of Helium-Based Plasma for Cutaneous Resurfacing and Subdermal Tightening
Sweitzer K, Obagi Z, Rahman T, Koltz PF, Barone F. (2021) The Safety and Efficacy of Helium-Based Plasma for Cutaneous Resurfacing and Subdermal Tightening. J Aesthet Reconstr Surg Vol.7 No.5:40.
Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy
Richard D. Gentile. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.
Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form
Thomas, M., D’silva, J., & Abraham, A. (2021). Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99947
Review of non-invasive and minimally invasive skin tightening techniques
Ghani S. Review of non-invasive and minimally invasive skin tightening techniques. Journal of Aesthetic Nursing 2019 8:Sup1, 26-33.
Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience
Vasilakis, V., Isakson, M.H., Yamin, F. et al. Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience. Aesth Plast Surg 44, 1596–1603 (2020). https://doi.org/10.1007/s00266-020-01857-1
Aesthetic Nonexcisional Arm Contouring
Saad Mohamed Saad Ibrahiem, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031
Subcutaneous Neck Skin Plasma Tightening
Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2 (2019) 89-95. DOI: 10.1016/j.yacs.2019.02.008.
Evolving Technologies for Tissue Cutting
Jundt JS, Marchena JM, Hanna I, Dhanda J, Breit MJ, Perry AP. Evolving Technologies for Tissue Cutting. Oral Maxillofac Surg Clin North Am. 2019 Nov;31(4):549-559. doi: 10.1016/j.coms.2019.07.009. Epub 2019 Aug 31. PMID: 31481290.
Posterior Torso and Buttocks Contour Enhancement
Zimmerman, Edward. “Posterior Torso and Buttocks Contour Enhancement”. Enhanced Liposuction – New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.
The Renuvion® APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma where coagulation/contraction of soft tissue is needed. Soft tissue includes subcutaneous tissue. The Renuvion APR Handpiece is intended for the coagulation of subcutaneous soft tissues following liposuction for aesthetic body contouring. The Renuvion APR Handpiece is indicated for use in subcutaneous dermatological and aesthetic procedures to improve the appearance of lax (loose) skin in the neck and submental region. The Renuvion APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma for cutting, coagulation and ablation of soft tissue during open surgical procedures. The Renuvion APR Handpiece is intended to be used with compatible electrosurgical generators owned by Apyx® Medical. Not all indications are approved in all markets; check with your local sales representative for further information.
As with any aesthetic procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use. Risk associated with the use of the Renuvion APR may include: helium embolism into the surgical site due to inadvertent introduction into the venous or arterial blood supply system, unintended burns (deep or superficial), pneumothorax, temporary or permanent nerve injury, ischemia, fibrosis, infection, pain, discomfort, gas buildup resulting in temporary and transient crepitus or pain, bleeding, hematoma, seroma, subcutaneous induration, pigmentation changes, increased healing time, scarring, asymmetry and/ or unacceptable cosmetic result. Please see the instructions for use for more detailed information.