PATIENTS PHYSICIANS

Contouring library

The following bibliography of published peer reviewed articles includes all uses of our technology. This is intended to be a forum for scientific exchange and thus this content may include unapproved uses. Not all markets have the same labeling, refer to the local Instructions for Use or contact your local representative for more information. All investigator disclosures are within the publications.

The Renuvion® APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma where coagulation/contraction of soft tissue is needed. Soft tissue includes subcutaneous tissue. The Renuvion APR Handpiece is intended for the coagulation of subcutaneous soft tissues following liposuction for aesthetic body contouring. The Renuvion APR Handpiece is indicated for use in subcutaneous dermatological and aesthetic procedures to improve the appearance of lax (loose) skin in the neck and submental region. The Renuvion APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma for cutting, coagulation and ablation of soft tissue during open surgical procedures. The Renuvion APR Handpiece is intended to be used with compatible electrosurgical generators owned by Apyx® Medical. Not all indications are approved in all markets; check with your local sales representative for further information.

As with any aesthetic procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use. Risk associated with the use of the Renuvion APR may include: helium embolism into the surgical site due to inadvertent introduction into the venous or arterial blood supply system, unintended burns (deep or superficial), pneumothorax, temporary or permanent nerve injury, ischemia, fibrosis, infection, pain, discomfort, gas buildup resulting in temporary and transient crepitus or pain, bleeding, hematoma, seroma, subcutaneous induration, pigmentation changes, increased healing time, scarring, asymmetry and/ or unacceptable cosmetic result. Please see the instructions for use for more detailed information.

 

Click on the categories below to view the related articles.

ABDOMEN, TORSO, BUTTOCKS

1. Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445

2. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.

3. De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.

4. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

5. Kleban SR, Bharti G, & Kortesis BG. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398

6. Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301

7. Zimmerman, Edward. "Posterior Torso and Buttocks Contour Enhancement". Enhanced Liposuction - New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

Aesthetic Body Contouring Following Liposuction

1. Akkary, E. (2022). Use of J Plasma® in Body Contouring. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_18

2. Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445

3. Cook J, Pozner JN, Turer DM, et al. Roundtable Discussion: Making Sense of Current Liposuction Technologies. Aesthet Surg J Open Forum. 2021;4:ojab045. Published 2021 Nov 9. doi:10.1093/asjof/ojab045

4. Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.

5. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.

6. De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.

7. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

8. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

9. Duncan DI. Helium Plasma-Driven Radiofrequency in Body Contouring. The Art of Body Contouring. Published March 8, 2019. DOI: 10.5772/intechopen.84207.

10. Duncan, Diane. (2020). Combining Helium Plasma-Driven Radiofrequency with Nanofat for Contouring. 10.5772/intechopen.91611.

11. Duncan, DI. The future of skin tightening: Mechanical or biological? Dermatological Reviews. 2020; 1: 128- 137. https://doi.org/10.1002/der2.40

12. Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001

13. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

14. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

15. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

16. Ghani S. Review of non-invasive and minimally invasive skin tightening techniques. Journal of Aesthetic Nursing 2019 8:Sup1, 26-33.

17. Hamlet, G., Mowlavi, A. (2022). Hi-Def Liposuction in Males and Females. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_13

18. Hoyos AE, Perez ME, Mogollon IR, Arcila A. Decision-Making Algorithm for Advanced Excisional Body Contouring: Dynamic Definition Solutions for Skin Laxity. Plast Reconstr Surg. 2022 Dec 1;150(6):1248-1259. doi: 10.1097/PRS.0000000000009740. Epub 2022 Sep 19. PMID: 36112807.

19. Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031

20. Jugenburg, M., Jalil, W. (2022). Liposuction: Principles and Techniques. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_4

21. Khanna, J., & Saheb-Al-Zamani, M. (2021). Enhanced Lipocontouring of the Arms. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.98807

22. Kleban, S. R. , Bharti, G., & Kortesis, B. G. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398

23. Kluska M, Deal RC, Summers K, Chang S. A Retrospective Review Comparing Renuvion Helium Plasma Radiofrequency with BodyTite Bipolar Radiofrequency after Liposuction or Body Contouring. Plastic & Reconstructive Surgery-Global Open 12(8):p e6024, August 2024. | DOI: 10.1097/GOX.0000000000006024

24. Malone, C.H., Walters, N., Stroh, R. et al. New Technologies in Skin Tightening. Curr Otorhinolaryngol Rep 9, 422–435 (2021). https://doi.org/10.1007/s40136-021-00371-5

25. Mata, C., Gadayev, M., Ferrara, G.P., Kesserwani, J. (2022). Hi- Def Liposuction- My Technique. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_12

26. Neinstein R, Funderburk CD. Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency. Advances in Cosmetic Surgery, Volume 3, Issue 1, 2020, Pages 173-188, ISSN 2542-4327, ISBN 9780323778282. https://doi.org/10.1016/j.yacs.2020.01.012.

27. Palmisano E, Di Biasio G. Minimally invasive management alternative for the treatment of patients with abdominal diastasis and dermal fat flap using the VER tactic: Vaser® + Endoscopy + Renuvion®. Rev Hispanoam Hernia. 2022;10(4):167-171

28. Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

29. Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

30. Shantharam R, et al., J Clin Dermatol Ther 2023, 9: 0128 DOI: 10.24966/CDT-8771/100128

31. Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081

32. Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112

33. Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301

34. Thomas M, D’silva J, Abraham A. (2021). Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99947

35. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153

36. Vasilakis, V., Isakson, M.H., Yamin, F. et al. Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience. Aesth Plast Surg 44, 1596–1603 (2020). https://doi.org/10.1007/s00266-020-01857-1

37. Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2 (2019) 89-95. DOI: 10.1016/j.yacs.2019.02.008.

38. Zimmerman, Edward. "Posterior Torso and Buttocks Contour Enhancement". Enhanced Liposuction - New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

Arms

1. Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.

2. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

3. Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031

4. Khanna, J., & Saheb-Al-Zamani, M. (2021). Enhanced Lipocontouring of the Arms. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.98807

5. Shantharam R, et al., J Clin Dermatol Ther 2023, 9: 0128 DOI: 10.24966/CDT-8771/100128

6. Vasilakis, V., Isakson, M.H., Yamin, F. et al. Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience. Aesth Plast Surg 44, 1596–1603 (2020). https://doi.org/10.1007/s00266-020-01857-1

Clinical Studies

1. Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.

2. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.

3. De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.

4. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

5. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

6. Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031

7. Kluska M, Deal RC, Summers K, Chang S. A Retrospective Review Comparing Renuvion Helium Plasma Radiofrequency with BodyTite Bipolar Radiofrequency after Liposuction or Body Contouring. Plastic & Reconstructive Surgery-Global Open 12(8):p e6024, August 2024. | DOI: 10.1097/GOX.0000000000006024

8. Leake D, Lee J. Applications of Helium Plasma in Rejuvenation of the Face and Neck [Internet]. Enhanced Liposuction - New Perspectives and Techniques. IntechOpen; 2022. Available from: http://dx.doi.org/10.5772/intechopen.100162

9. Moncada S, Nichols C. Helium Plasma-Assisted Breast Reduction: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac041, https://doi.org/10.1093/asjof/ojac041

10. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

11. Ruff PG, Doolabh V, Zimmerman E, Gentile R. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews 2020; 1-7. https://doi.org/10.1002/der2.34

12. Ruff PG, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

13. Ruff PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

14. Shantharam R, et al., J Clin Dermatol Ther 2023, 9: 0128 DOI: 10.24966/CDT-8771/100128

15. Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081

16. Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112

17. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153

18. Zorrilla AM, Sanchez-Covarrubias AP, Martin K, Rodriguez M. Pain Management and Opioid Consumption After Outpatient Cosmetic Surgery. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221116529

Contractile Effects and Tissue Remodeling

1. Canter HI, Ismayilzada M. Minimally Invasive Treatments for the Aging Face. Academic Press, Beauty, Aging, and AntiAging, 2023, Pages 211-221. https://doi.org/10.1016/B978-0-323-98804-9.00021-9

2. Dayan E, Theodorou S. Not all Radiofrequency Devices Are Created Equal: A Thermal Assessment. Plast Reconstr Surg Glob Open. 2022 Feb 4;10(2):e4077. doi: 10.1097/GOX.0000000000004077. PMID: 35141101; PMCID: PMC8820913.

3. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

4. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

5. Duncan DI. Helium Plasma-Driven Radiofrequency in Body Contouring. The Art of Body Contouring. Published March 8, 2019. DOI: 10.5772/intechopen.84207.

6. Duncan DI, Roman, S. Helium Plasma Subdermal Tissue Contraction Method of Action. BioMedical Journal of Scientific & Technical Research. October 19, 2020; DOI: 10.26717/BJSTR.2020.31.005075.

7. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

8. Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001

9. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

10. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

11. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

12. Ruff IV, PG. Thermal Effects of Percutaneous Application of Plasma/Radiofrequency Energy on Porcine Dermis & Fibroseptal Network. JCD, 2020. DOI: 10.1111/jocd.13845

13. Thomas M, D’silva J, Abraham A. (2021). Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99947

Facelift

1. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

2. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

3. Gentile RD. Tesla Facelifting Using Energy Devices during Rhytidectomy. Facial Plast Surg 2022; 38(06): 668-678. DOI: 10.1055/s-0042-1757758

4. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

Face and Neck (Subdermal Treatment)

1. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

2. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

3. Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001

4. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

5. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

6. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

7. Leake D, Lee J. Applications of Helium Plasma in Rejuvenation of the Face and Neck [Internet]. Enhanced Liposuction - New Perspectives and Techniques. IntechOpen; 2022. Available from: http://dx.doi.org/10.5772/intechopen.100162

8. Lotfi M, Khani M, Shokri B. A Review of Cold Atmospheric Plasma Applications in Dermatology and Aesthetics. Plasma Medicine, Volume 13, Issue 1, 2023, pp. 39-63. DOI: 10.1615/PlasmaMed.2023049359.

9. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

10. Sturm A, Shokri T, Ducic Y. Nonsurgical Rejuvenation of the Neck. Facial Plast Surg Clin North Am. 2022 Aug;30(3):407-417. doi: 10.1016/j.fsc.2022.03.014. PMID: 35934442.

11. Wang MW, Rodman RE. Gender Facial Affirmation Surgery; Techniques for Feminizing the Chin. Facial Plast Surg Clin North Am. 2023 Aug;31(3):419-431. doi: 10.1016/j.fsc.2023.04.006. PMID: 37348985.

12. Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2 (2019) 89-95. DOI: 10.1016/j.yacs.2019.02.008.

Fat Graft Viability

1. Ruff, PG., Sterodimas, A. Enhanced Fat Graft Viability and Remodeling Using a Helium-based Radiofrequency Device to Prepare the Recipient Site. Aesth Plast Surg (2023). https://doi.org/10.1007/s00266-023-03749-6

Gynecomastia

1. Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

Rhinophyma

1. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

Safety

1. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

2. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

3. Kluska M, Deal RC, Summers K, Chang S. A Retrospective Review Comparing Renuvion Helium Plasma Radiofrequency with BodyTite Bipolar Radiofrequency after Liposuction or Body Contouring. Plastic & Reconstructive Surgery-Global Open 12(8):p e6024, August 2024. | DOI: 10.1097/GOX.0000000000006024

4. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

5. Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

6. Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

7. Ruff IV, PG, Doolabh V, Zimmerman E, Gentile R. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews 2020; 1-7. https://doi.org/10.1002/der2.34

8. Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081

9. Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112

10. Zorrilla AM, Sanchez-Covarrubias AP, Martin K, Rodriguez M. Pain Management and Opioid Consumption After Outpatient Cosmetic Surgery. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221116529

Subdermal Use – Renuvion Only

1. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

2. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

3. Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

Surgical, Cutting, Flaps

1. Elmore L, Minissale NJ, Israel L, Katz Z, Safran J, Barba A, Austin L, Schaer TP, Freeman TA. Evaluating the Healing Potential of J-Plasma Scalpel-Created Surgical Incisions in Porcine and Rat Models. Biomedicines 2024, 12, 277. https://doi.org/10.3390/biomedicines12020277

2. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

3. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

4. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

5. Gentile R. Ultrasound-Assisted Rhytidectomy Including Sub-SMAS and Subplatysmal Dissection. Facial Plast Surg 2020; 36(04): 430-446. DOI: 10.1055/s-0040-1714119

6. Jundt JS, Marchena JM, Hanna I, Dhanda J, Breit MJ, Perry AP. Evolving Technologies for Tissue Cutting. Oral Maxillofac Surg Clin North Am. 2019 Nov;31(4):549-559. doi: 10.1016/j.coms.2019.07.009. Epub 2019 Aug 31. PMID: 31481290.

7. Moncada S, Nichols C. Helium Plasma-Assisted Breast Reduction: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac041, https://doi.org/10.1093/asjof/ojac041

8. Palmisano E, Di Biasio G. Minimally invasive management alternative for the treatment of patients with abdominal diastasis and dermal fat flap using the VER tactic: Vaser® + Endoscopy + Renuvion®. Rev Hispanoam Hernia. 2022;10(4):167-171

9. Pinelli M, Starnoni M, De Santis G. The Use of Cold Atmospheric Plasma Device in Flap Elevation. Plast Reconstr Surg Glob Open 2020;8:e2815; doi: 10.1097/GOX.0000000000002815.

10. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153

ABDOMEN, TORSO, BUTTOCKS

  • Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445
  • De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010
  • De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.
  • Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849
  • Kleban SR, Bharti G, & Kortesis BG. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398
  • Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301
  • Zimmerman, Edward. "Posterior Torso and Buttocks Contour Enhancement". Enhanced Liposuction - New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

ABDOMEN, TORSO, BUTTOCKS

  • Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445
  • De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.
  • De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.
  • Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849
  • Kleban SR, Bharti G, & Kortesis BG. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398
  • Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301
  • Zimmerman, Edward. "Posterior Torso and Buttocks Contour Enhancement". Enhanced Liposuction - New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

Aesthetic Body Contouring Following Liposuction

  • Akkary, E. (2022). Use of J Plasma in Body Contouring. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_18
  • Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445
  • Cook J, Pozner JN, Turer DM, et al. Roundtable Discussion: Making Sense of Current Liposuction Technologies. Aesthet Surg J Open Forum. 2021;4:ojab045. Published 2021 Nov 9. doi:10.1093/asjof/ojab045
  • Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.
  • De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.
  • De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.
  • Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.
  • Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849
  • Duncan DI. Helium Plasma-Driven Radiofrequency in Body Contouring. The Art of Body Contouring. Published March 8, 2019. DOI: 10.5772/intechopen.84207.
  • Duncan, Diane. (2020). Combining Helium Plasma-Driven Radiofrequency with Nanofat for Contouring. 10.5772/intechopen.91611.
  • Duncan, DI. The future of skin tightening: Mechanical or biological? Dermatological Reviews. 2020; 1: 128- 137. https://doi.org/10.1002/der2.40
  • Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001
  • Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.
  • Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.
  • Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.
  • Ghani S. Review of non-invasive and minimally invasive skin tightening techniques. Journal of Aesthetic Nursing 2019 8:Sup1, 26-33.
  • Hamlet, G., Mowlavi, A. (2022). Hi-Def Liposuction in Males and Females. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_13
  • Hoyos AE, Perez ME, Mogollon IR, Arcila A. Decision-Making Algorithm for Advanced Excisional Body Contouring: Dynamic Definition Solutions for Skin Laxity. Plast Reconstr Surg. 2022 Dec 1;150(6):1248-1259. doi: 10.1097/PRS.0000000000009740. Epub 2022 Sep 19. PMID: 36112807.
  • Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031
  • Jugenburg, M., Jalil, W. (2022). Liposuction: Principles and Techniques. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_4
  • Khanna, J., & Saheb-Al-Zamani, M. (2021). Enhanced Lipocontouring of the Arms. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.98807
  • Kleban, S. R. , Bharti, G., & Kortesis, B. G. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398
  • Malone, C.H., Walters, N., Stroh, R. et al. New Technologies in Skin Tightening. Curr Otorhinolaryngol Rep 9, 422–435 (2021). https://doi.org/10.1007/s40136-021-00371-5
  • Mata, C., Gadayev, M., Ferrara, G.P., Kesserwani, J. (2022). Hi- Def Liposuction- My Technique. In: Thomas, M., D'silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_12
  • Neinstein R, Funderburk CD. Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency. Advances in Cosmetic Surgery, Volume 3, Issue 1, 2020, Pages 173-188, ISSN 2542-4327, ISBN 9780323778282. https://doi.org/10.1016/j.yacs.2020.01.012.
  • Palmisano E, Di Biasio G. Minimally invasive management alternative for the treatment of patients with abdominal diastasis and dermal fat flap using the VER tactic: Vaser® + Endoscopy + Renuvion®. Rev Hispanoam Hernia. 2022;10(4):167-171
  • Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.
  • Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064
  • Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081
  • Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112
  • Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301
  • Thomas M, D’silva J, Abraham A. (2021). Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form. In (Ed.), Enhanced Liposuction - New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99947
  • Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153
  • Vasilakis, V., Isakson, M.H., Yamin, F. et al. Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience. Aesth Plast Surg 44, 1596–1603 (2020). https://doi.org/10.1007/s00266-020-01857-1
  • Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2 (2019) 89-95. DOI: 10.1016/j.yacs.2019.02.008.
  • Zimmerman, Edward. "Posterior Torso and Buttocks Contour Enhancement". Enhanced Liposuction - New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

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The Renuvion APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma where coagulation/contraction of soft tissue is needed. Soft tissue includes subcutaneous tissue. The Renuvion APR Handpiece is intended for the coagulation of subcutaneous soft tissues following liposuction for aesthetic body contouring. The Renuvion APR Handpiece is indicated for use in subcutaneous dermatological and aesthetic procedures to improve the appearance of lax (loose) skin in the neck and submental region. The Renuvion APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma for cutting, coagulation and ablation of soft tissue during open surgical procedures. The Renuvion APR Handpiece is intended to be used with compatible electrosurgical generators owned by Apyx® Medical. Not all indications are approved in all markets; check with your local sales representative for further information.

As with any aesthetic procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use. Risk associated with the use of the Renuvion APR may include: helium embolism into the surgical site due to inadvertent introduction into the venous or arterial blood supply system, unintended burns (deep or superficial), pneumothorax, temporary or permanent nerve injury, ischemia, fibrosis, infection, pain, discomfort, gas buildup resulting in temporary and transient crepitus or pain, bleeding, hematoma, seroma, subcutaneous induration, pigmentation changes, increased healing time, scarring, asymmetry and/ or unacceptable cosmetic result. Please see the instructions for use for more detailed information.

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